Region does not seem to be available error for AWS module boto.ec2

When you have this error, there is a good chance that your boto version is outdated. You will have to update the boto version by executing the below command:

pip install boto

This will install latest version of Boto framework which is 2.48.0. 

you can confirm by executing the below command:

pip list boto | grep boto

boto (2.48.0)

boto3 (1.5.22)

botocore (1.8.36)